Cellular and Phenotypic Plasticity in Cancer

• मुख्य लेखक: Petranel Theresa Ferrao (auth)
• अन्य लेखक: Andreas Behren (auth), Erik Thompson (auth), Robin Anderson (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2015
• श्रृंखला: Frontiers Research Topics
• विषय: Medicine; crosstalk; Immune System; Phenotype-switching; plasticity; Exosomes; EMT; Therapy-resistance; signalling; heterogeneity; Cancer
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

The process of Epithelial-Mesenchymal-Transition (EMT) is known to result in a phenotype change in cells from a proliferative state to a more invasive state. EMT has been reported to drive the metastatic spread of various cancers and has also been associated with drug resistance to cytotoxics and ta...