Metals and neurodegeneration: Restoring the balance

• 1. autor: Katja M. Kanninen (auth)
• Kolejni autorzy: Anthony R. White (auth), Peter J. Crouch (auth)
• Format: Elektroniczne Rozdział
• Język: angielski
• Wydane: Frontiers Media SA 2016
• Seria: Frontiers Research Topics
• Hasła przedmiotowe: Neurosciences; Brain; neurodegenerative disease; Neurons; Metals; Iron; Copper; Alzheimer's disease; Zinc; Manganese
• Dostęp online: DOAB: download the publication; DOAB: description of the publication

Biometals such as copper, zinc and iron have key biological functions, however, aberrant metabolism can lead to detrimental effects on cell function and survival. These biometals have important roles in the brain, driving cellular respiration, antioxidant activity, intracellular signaling and many a...