Molecular Chaperones and Neurodegeneration

• מחבר ראשי: Cintia Roodveldt (auth)
• מחברים אחרים: Janice E. Braun (auth), Tiago F. Outeiro (auth)
• פורמט: אלקטרוני Book Chapter
• שפה: אנגלית
• יצא לאור: Frontiers Media SA 2017
• סדרה: Frontiers Research Topics
• נושאים: Neurosciences; molecular chaperone; therapeutics; neurodegenerative disease; heat-shock response; protein misfolding; neuroprotection; neurodegeneration; heat-shock protein; proteostasis; amyloid protein
• גישה מקוונת: DOAB: download the publication; DOAB: description of the publication

Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered...