Molecular Mechanism of Alzheimer's Disease

• প্রধান লেখক: Macreadie, Ian (auth)
• বিন্যাস: বৈদ্যুতিক গ্রন্থের অধ্যায়
• ভাষা: ইংরেজি
• প্রকাশিত: MDPI - Multidisciplinary Digital Publishing Institute 2019
• বিষয়গুলি: Biology, life sciences; HOTAIR; neurosciences; sleep disturbance; positron emission tomography (PET); vitamin B complex; neurodegeneration; Tau; miR-15/107; default-mode network; complement receptor 1; neuronal differentiation; epigenetics; brain glucose metabolism; oligomerization; genetic risk; A?O receptors; prion; ryanodine receptor; type 3 diabetes; complement; cognitive behavioral therapy for insomnia; cognitive function; epigenome-wide association study; Alzheimer's disease; calcium signaling; ?-secretase; tau; Prolyl isomerases; NEAT1; complement C3b/C4b receptor; proteostasis; amyloid beta; yeast; slow-wave sleep; amyloid ?; nutrition; 4; protein aggregation; apolipoprotein E; dementia; MALAT1; inositol 1; lncRNAs; molecular biology; methylenetetrahydrofolate reductase MTHFR gene; 5-trisphosphate receptor; CR1 density; miR-34c; aggregation; heat shock protein; dendritic spine; S-adenosylmethionine; beta amyloid; ion channel; inflammation; sleep fragmentation; cystathionine-?-lyase CTH gene; DNA methylation; heat shock response; microglia; drug target discovery; amyloid-? oligomer; therapy; CR1 length polymorphism; methylome; APOE gene; ubiquitin; magnetic resonance imaging (MRI); neuronal degeneration; type 2 diabetes; Pin1; mild cognitive impairment; dairy products; endoplasmic reticulum; oxidative stress; Hispanics; CDK5R1
• অনলাইন ব্যবহার করুন: DOAB: download the publication; DOAB: description of the publication

সংক্ষিপ্ত

Alzheimer's disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer's disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue.

দৈহিক বর্ননা

1 electronic resource (228 p.)

আইসবিএন

books978-3-03921-408-2
9783039214082
9783039214075

প্রবেশাধিকার

Open Access