Multidrug resistance in Cancer: Pharmacological Strategies from Basic Research to Clinical Issues

More than 40 years ago, the observation that doxorubicin-resistant tumor cells were cross-resistant to several structurally different anticancer agents was the first step in the discovery of P-glycoprotein (P-gp). P-gp belongs to the superfamily of ATP-binding cassette (ABC) transporters;its overexp...

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Príomhchruthaitheoir: Chiara Riganti (auth)
Rannpháirtithe: Enrico Mini (auth), Stefania Nobili (auth)
Formáid: Leictreonach Caibidil leabhair
Teanga:Béarla
Foilsithe / Cruthaithe: Frontiers Media SA 2015
Sraith:Frontiers Research Topics
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