Myelin-Mediated Inhibition of Axonal Regeneration: Past, Present, and Future

• 1. Verfasser: Wilfredo Mellado (auth)
• Weitere Verfasser: Sari Hannila (auth)
• Format: Elektronisch Buchkapitel
• Sprache: Englisch
• Veröffentlicht: Frontiers Media SA 2017
• Schriftenreihe: Frontiers Research Topics
• Schlagworte: Neurosciences; MAG; Omgp; axonal regeneration; myelin-associated inhibitors; CNS regeneration; Nogo; cAMP
• Online-Zugang: DOAB: download the publication; DOAB: description of the publication

Pioneering studies conducted in the 1980's laid the foundation for the hypothesis that axonal regeneration is limited by CNS myelin, and the identification of myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte myelin glycoprotein (OMgp) as inhibitors of neurite outgrowth firmly est...