Myelin-Mediated Inhibition of Axonal Regeneration: Past, Present, and Future

• Hoofdauteur: Wilfredo Mellado (auth)
• Andere auteurs: Sari Hannila (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2017
• Reeks: Frontiers Research Topics
• Onderwerpen: Neurosciences; MAG; Omgp; axonal regeneration; myelin-associated inhibitors; CNS regeneration; Nogo; cAMP
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Pioneering studies conducted in the 1980's laid the foundation for the hypothesis that axonal regeneration is limited by CNS myelin, and the identification of myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte myelin glycoprotein (OMgp) as inhibitors of neurite outgrowth firmly est...