Programming the HPA-axis by early life experience: Mechanisms of stress susceptibility and adaptation

• Hoofdauteur: Nikolaos P. Daskalakis (auth)
• Andere auteurs: Rachel Yehuda (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2015
• Reeks: Frontiers Research Topics
• Onderwerpen: Medicine; HPA axis; Vulnerability; resilience; early life stress; materna
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later...