The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance

• मुख्य लेखक: Geraldo Aleixo Passos (auth)
• अन्य लेखक: Ernna Herida Oliveira (auth), Daniella Areas Mendes-da-Cruz (auth)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2016
• श्रृंखला: Frontiers Research Topics
• विषय: Medicine; thymic crosstalk; Central Tolerance; promiscuous gene expression; Aire gene; cell-cell interaction; thymocyte; microRNA; Thymic B cell; Chemokines; Thymus
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mT...