Ubiquitin and Ubiquitin-Relative SUMO in DNA Damage Response

• 第一著者: Kristijan Ramadan (auth)
• その他の著者: Ivan Dikic (auth)
• フォーマット: 電子媒体 図書の章
• 言語: 英語
• 出版事項: Frontiers Media SA 2018
• シリーズ: Frontiers Research Topics
• 主題: Genetics (non-medical); Ubiquitin; genome stability; Ubiquitination; SUMO; DNA damage response; Sumoylation; Cancer
• オンライン･アクセス: DOAB: download the publication; DOAB: description of the publication

DNA damage response (DDR) is a term that includes a variety of highly sophisticated mechanisms that cells have evolved in safeguarding the genome from the deleterious consequences of DNA damage. It is estimated that every single cell receives tens of thousands of DNA lesions per day. Failure of DDR...