Ubiquitin and Ubiquitin-Relative SUMO in DNA Damage Response

• Yazar: Kristijan Ramadan (auth)
• Diğer Yazarlar: Ivan Dikic (auth)
• Materyal Türü: Elektronik Kitap Bölümü
• Dil: İngilizce
• Baskı/Yayın Bilgisi: Frontiers Media SA 2018
• Seri Bilgileri: Frontiers Research Topics
• Konular: Genetics (non-medical); Ubiquitin; genome stability; Ubiquitination; SUMO; DNA damage response; Sumoylation; Cancer
• Online Erişim: DOAB: download the publication; DOAB: description of the publication

DNA damage response (DDR) is a term that includes a variety of highly sophisticated mechanisms that cells have evolved in safeguarding the genome from the deleterious consequences of DNA damage. It is estimated that every single cell receives tens of thousands of DNA lesions per day. Failure of DDR...