G Protein-Coupled Receptor Kinases (GRKs) and Beta-Arrestins: New Insights into Disease Regulators

• Beste egile batzuk: Hattori, Yuichi (Argitaratzailea), Michel, Martin C. (Argitaratzailea)
• Formatua: Baliabide elektronikoa Liburu kapitulua
• Hizkuntza: ingelesa
• Argitaratua: Frontiers Media SA 2020
• Gaiak: Science: general issues; Pharmacology; GRK; beta-arrestins; cardiovascular; inflammation; cancer
• Sarrera elektronikoa: DOAB: download the publication; DOAB: description of the publication

G protein-coupled receptor kinases (GRKs) and arrestins were initially identified as a pivotal player in the process of desensitization of agonist-activated G protein-coupled receptors (GPCRs). However, growing evidence suggests GRKs and arrestins fulfill a vital role in regulating a variety of cell...