The Protective Effect of Radicicol Against Renal Ischemia-Reperfusion Injury in Mice

• Главные авторы: Hiroko Sonoda (Автор), Worapat Prachasilchai (Автор), Hiroaki Kondo (Автор), Naoko Yokota-Ikeda (Автор), Sayaka Oshikawa (Автор), Katsuaki Ito (Автор), Masahiro Ikeda (Автор)
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• Опубликовано: Elsevier, 2010-01-01T00:00:00Z.
• Предметы: article
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Overexpression of heat shock protein 70 kDa (HSP70) is known to confer cellular protection against ischemia-reperfusion (I/R) injury. Radicicol, a HSP90 inhibitor, has been reported to induce the expression of HSP70 protein. Here we studied whether radicicol attenuated renal I/R injury in vivo. Trea...