An Effective Sodium-Dependent Glucose Transporter 2 Inhibition, Canagliflozin, Prevents Development of Hypertensive Heart Failure in Dahl Salt-Sensitive Rats

• मुख्य लेखकों: Lili He (लेखक), Sai Ma (लेखक), Qingjuan Zuo (लेखक), Guorui Zhang (लेखक), Zhongli Wang (लेखक), Tingting Zhang (लेखक), Jianlong Zhai (लेखक), Yifang Guo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: The aim of the study was to investigate the protective effect of canagliflozin (CANA) on myocardial metabolism and heart under stress overload and to further explore its possible molecular mechanism.Methods: High-salt diet was used to induce heart failure with preserved ejection fraction...