Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells

• Main Authors: Chun-Hong Yu (Author), Shui-Qing Yang (Author), Lei Li (Author), Yu Xin (Author), Fang Zhang (Author), Xiao-Fan Liu (Author), Zong-Chun Yi (Author)
• 格式: 圖書
• 出版: BMC, 2022-04-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Abstract Background Hydroquinone (HQ) is a phenolic metabolite of benzene with a potential risk for hematological disorders and hematotoxicity in humans. In the present study, an integrative analysis of microRNA (miRNA) and mRNA expressions was performed to identify potential pathways and miRNA-mRNA...