Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells

• المؤلفون الرئيسيون: Chun-Hong Yu (مؤلف), Shui-Qing Yang (مؤلف), Lei Li (مؤلف), Yu Xin (مؤلف), Fang Zhang (مؤلف), Xiao-Fan Liu (مؤلف), Zong-Chun Yi (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2022-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Hydroquinone (HQ) is a phenolic metabolite of benzene with a potential risk for hematological disorders and hematotoxicity in humans. In the present study, an integrative analysis of microRNA (miRNA) and mRNA expressions was performed to identify potential pathways and miRNA-mRNA...