Structure-based design and optimization lead to the identification of novel dihydrothiopyrano[3,2-d]pyrimidine derivatives as potent HIV-1 inhibitors against drug-resistant variants

With our continuous endeavors in seeking potent anti-HIV-1 agents, we reported here the discovery, biological characterization, and druggability evaluation of a class of nonnucleoside reverse transcriptase inhibitors. To fully explore the chemical space of the NNRTI-binding pocket, novel series of d...

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में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zhao Wang (लेखक), Heng Zhang (लेखक), Zhen Gao (लेखक), Zihao Sang (लेखक), Erik De Clercq (लेखक), Christophe Pannecouque (लेखक), Dongwei Kang (लेखक), Peng Zhan (लेखक), Xinyong Liu (लेखक)
स्वरूप: पुस्तक
प्रकाशित: Elsevier, 2024-03-01T00:00:00Z.
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