Solubility enhancement of carvedilol using drug-drug cocrystallization with hydrochlorothiazide

Abstract Background Increasing hydrophilicity of poorly water-soluble drugs is a major challenge in drug discovery and development. Cocrystallization is one of the techniques to enhance the hydrophilicity of such drugs. Carvedilol (CAR), a nonselective beta/alpha1 blocker, used in the treatment of m...

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Main Authors: Shivarani Eesam (Author), Jaswanth S. Bhandaru (Author), Chandana Naliganti (Author), Ravi Kumar Bobbala (Author), Raghuram Rao Akkinepally (Author)
Format: Book
Published: SpringerOpen, 2020-11-01T00:00:00Z.
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Call Number: A1234.567
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