Clostridium difficile suppresses colonic vasoactive intestinal peptide associated with altered motility

• প্রধান লেখক: A. Nassif (Author), W. E. Longo (Author), R. Sexe (Author), M. Stratton (Author), J. Standeven (Author), A. M. Vernava (Author), D. L. Kaminski (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Hindawi Limited, 1995-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

We investigated whether Clostridium difficile toxin alters colonic tissue levels of vasoactive intestinal peptide (VIP) at the expense of changes in colonic motility in the isolated perfused rabbit left colon. Colonic inflammation was induced by the intracolonic administration of 10−8 M C. difflcile...