Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma

• Main Authors: Caroline E. Nunes-Xavier (Author), Olaia Aurtenetxe (Author), Laura Zaldumbide (Author), Ricardo López-Almaraz (Author), Asier Erramuzpe (Author), Jesús M. Cortés (Author), José I. López (Author), Rafael Pulido (Author)
• Format: Book
• Published: BMC, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the function and expression of the non-receptor PTPN1 on human NB cell lines...