Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma

• المؤلفون الرئيسيون: Caroline E. Nunes-Xavier (مؤلف), Olaia Aurtenetxe (مؤلف), Laura Zaldumbide (مؤلف), Ricardo López-Almaraz (مؤلف), Asier Erramuzpe (مؤلف), Jesús M. Cortés (مؤلف), José I. López (مؤلف), Rafael Pulido (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2019-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the function and expression of the non-receptor PTPN1 on human NB cell lines...