Pharmacogenomics polygenic risk score: Ready or not for prime time?

• Asıl Yazarlar: Sonal Singh (Yazar), Gabriele Stocco (Yazar), Katherine N. Theken (Yazar), Alyson Dickson (Yazar), QiPing Feng (Yazar), Jason H. Karnes (Yazar), Jonathan D. Mosley (Yazar), Nihal El Rouby (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2024-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Pharmacogenomic Polygenic Risk Scores (PRS) have emerged as a tool to address the polygenic nature of pharmacogenetic phenotypes, increasing the potential to predict drug response. Most pharmacogenomic PRS have been extrapolated from disease‐associated variants identified by genome wide ass...