Pharmacogenomics polygenic risk score: Ready or not for prime time?

• Päätekijät: Sonal Singh (Tekijä), Gabriele Stocco (Tekijä), Katherine N. Theken (Tekijä), Alyson Dickson (Tekijä), QiPing Feng (Tekijä), Jason H. Karnes (Tekijä), Jonathan D. Mosley (Tekijä), Nihal El Rouby (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2024-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Pharmacogenomic Polygenic Risk Scores (PRS) have emerged as a tool to address the polygenic nature of pharmacogenetic phenotypes, increasing the potential to predict drug response. Most pharmacogenomic PRS have been extrapolated from disease‐associated variants identified by genome wide ass...