Optimization of In Vivo Electroporation Conditions and Delivery of DNA Vaccine Encoding SARS-CoV-2 RBD Using the Determined Protocol

• मुख्य लेखकों: Denis Nikolaevich Kisakov (लेखक), Lyubov Alexandrovna Kisakova (लेखक), Maria Borisovna Borgoyakova (लेखक), Ekaterina Vladimirovna Starostina (लेखक), Oleg Svyatoslavovich Taranov (लेखक), Elena Konstantinovna Ivleva (लेखक), Oleg Viktorovich Pyankov (लेखक), Anna Vladimirovna Zaykovskaya (लेखक), Dmitry Nikolaevich Shcherbakov (लेखक), Andrey Pavlovich Rudometov (लेखक), Nadezda Borisovna Rudometova (लेखक), Natalia Vyacheslavovna Volkova (लेखक), Vadim Nikolaevich Gureev (लेखक), Alexander Alexeyevich Ilyichev (लेखक), Larisa Ivanovna Karpenko (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Vaccination against SARS-CoV-2 and other viral infections requires safe, effective, and inexpensive vaccines that can be rapidly developed. DNA vaccines are candidates that meet these criteria, but one of their drawbacks is their relatively weak immunogenicity. Electroporation (EP) is an effective w...