HLH-30/TFEB modulates autophagy to improve proteostasis in Aβ transgenic Caenorhabditis elegans

• Main Authors: Hongru Lin (Author), Chen Zhang (Author), Yehui Gao (Author), Yi Zhou (Author), Botian Ma (Author), Jinyun Jiang (Author), Xue Long (Author), Nuerziya Yimamu (Author), Kaixin Zhong (Author), Yingzi Li (Author), Xianghuan Cui (Author), Hongbing Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is a complex neurodegenerative disease that affects elderly individuals, characterized by senile plaques formed by extracellular amyloid beta (Aβ). Autophagy dysfunction is a manifestation of protein homeostasis imbalance in patients with AD, but its relationship with A...