HLH-30/TFEB modulates autophagy to improve proteostasis in Aβ transgenic Caenorhabditis elegans

• Автори: Hongru Lin (Автор), Chen Zhang (Автор), Yehui Gao (Автор), Yi Zhou (Автор), Botian Ma (Автор), Jinyun Jiang (Автор), Xue Long (Автор), Nuerziya Yimamu (Автор), Kaixin Zhong (Автор), Yingzi Li (Автор), Xianghuan Cui (Автор), Hongbing Wang (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Alzheimer's disease (AD) is a complex neurodegenerative disease that affects elderly individuals, characterized by senile plaques formed by extracellular amyloid beta (Aβ). Autophagy dysfunction is a manifestation of protein homeostasis imbalance in patients with AD, but its relationship with A...