Immunogenicity of WHO-17D and Brazilian 17DD yellow fever vaccines: a randomized trial

• Main Authors: Camacho Luiz Antonio Bastos (Author), Freire Marcos da Silva (Author), Leal Maria da Luz Fernandes (Author), Aguiar Savitri Gomes de (Author), Nascimento Jussara Pereira do (Author), Iguchi Takumi (Author), Lozana José de Azevedo (Author), Farias Roberto Henrique Guedes (Author)
• Format: Book
• Published: Universidade de São Paulo, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

OBJECTIVE: To compare the immunogenicity of three yellow fever vaccines from WHO-17D and Brazilian 17DD substrains (different seed-lots). METHODS: An equivalence trial was carried out involving 1,087 adults in Rio de Janeiro. Vaccines produced by Bio-Manguinhos, Fiocruz (Rio de Janeiro, Brazil) were...