Immunogenicity of WHO-17D and Brazilian 17DD yellow fever vaccines: a randomized trial

• Главные авторы: Camacho Luiz Antonio Bastos (Автор), Freire Marcos da Silva (Автор), Leal Maria da Luz Fernandes (Автор), Aguiar Savitri Gomes de (Автор), Nascimento Jussara Pereira do (Автор), Iguchi Takumi (Автор), Lozana José de Azevedo (Автор), Farias Roberto Henrique Guedes (Автор)
• Формат: ‌
• Опубликовано: Universidade de São Paulo, 2004-01-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

OBJECTIVE: To compare the immunogenicity of three yellow fever vaccines from WHO-17D and Brazilian 17DD substrains (different seed-lots). METHODS: An equivalence trial was carried out involving 1,087 adults in Rio de Janeiro. Vaccines produced by Bio-Manguinhos, Fiocruz (Rio de Janeiro, Brazil) were...