Inonotus obliquus Polysaccharide Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Cancer in Mice via Activation of the NLRP3 Inflammasome

• Principais autores: Jiawei Li (Autor), Chao Qu (Autor), Fangfang Li (Autor), Yifang Chen (Autor), Jinjuan Zheng (Autor), Yao Xiao (Autor), Quanxin Jin (Autor), Guihua Jin (Autor), Xuezhu Huang (Autor), Dan Jin (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Inonotus obliquus polysaccharide (IOP), the primary constituent of the parasitic fungus Inonotus obliquus, has anti-tumor, anti-inflammatory, anti-oxidation effects. However, the roles of IOP on colitis-associated cancer (CAC) are still unclear. Herein, we tested the efficacy of IOP using a mouse mo...