Inonotus obliquus Polysaccharide Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Cancer in Mice via Activation of the NLRP3 Inflammasome

• Main Authors: Jiawei Li (Author), Chao Qu (Author), Fangfang Li (Author), Yifang Chen (Author), Jinjuan Zheng (Author), Yao Xiao (Author), Quanxin Jin (Author), Guihua Jin (Author), Xuezhu Huang (Author), Dan Jin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inonotus obliquus polysaccharide (IOP), the primary constituent of the parasitic fungus Inonotus obliquus, has anti-tumor, anti-inflammatory, anti-oxidation effects. However, the roles of IOP on colitis-associated cancer (CAC) are still unclear. Herein, we tested the efficacy of IOP using a mouse mo...