Numerical simulation method for the assessment of the effect of molar activity on the pharmacokinetics of radioligands in small animals
Abstract Background It is well recognized that the molar activity of a radioligand is an important pharmacokinetic parameter, especially in positron emission tomography (PET) of small animals. Occupation of a significant number of binding sites by radioligand molecules results in low radioligand acc...
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SpringerOpen,
2024-11-01T00:00:00Z.
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