Novel N-(pyrimidin-4-yl)thiazol-2-amine derivatives as dual-action hypoglycemic agents that activate GK and PPARγ
A series of novel N-(pyrimidin-4-yl)thiazol-2-amine derivatives have been synthesized and evaluated as glucokinase (GK) activators. Ethyl 2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl-amino)thiazole-5-carboxylate was found to be a potent dual-acting hypoglycemic agent activating bot...
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主要な著者: | , , , , , , , , |
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フォーマット: | 図書 |
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Elsevier,
2011-10-01T00:00:00Z.
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請求記号: |
A1234.567 |
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所蔵 1 | 利用可 |