Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN

• मुख्य लेखकों: Weilian Liang (लेखक), Yang Chen (लेखक), Hanzhe Liu (लेखक), Hui Zhao (लेखक), Tingting Luo (लेखक), Hokeung Tang (लेखक), Xiaocheng Zhou (लेखक), Erhui Jiang (लेखक), Zhe Shao (लेखक), Ke Liu (लेखक), Zhengjun Shang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Nature Publishing Group, 2022-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Tumor volume increases continuously in the advanced stage, and aside from the self-renewal of tumor cells, whether the oncogenic transformation of surrounding normal cells is involved in this process is currently unclear. Here, we show that oral squamous cell carcinoma (OSCC)-derived small...