Baicalin circumvents anti-PD-1 resistance by regulating the gut microbiota metabolite short-chain fatty acids

• मुख्य लेखकों: Zhang Yu (लेखक), Liu Xiaojia (लेखक), Zhao Wei (लेखक), Zhang Jian (लेखक), Wang Aiting (लेखक), Wang Jing (लेखक), Yang Lin (लेखक), Cao Bangwei (लेखक), Yan Dan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Baicalin is a small molecule medication used to treat hepatitis. Our research group discovered that administering baicalin orally to mice following fecal microbiota transplantation from patients resistant to ICIs supported anti-PD-1 activity. However, the precise mechanisms behind this effect are pr...