Baicalin circumvents anti-PD-1 resistance by regulating the gut microbiota metabolite short-chain fatty acids

• প্রধান লেখক: Zhang Yu (লেখক), Liu Xiaojia (লেখক), Zhao Wei (লেখক), Zhang Jian (লেখক), Wang Aiting (লেখক), Wang Jing (লেখক), Yang Lin (লেখক), Cao Bangwei (লেখক), Yan Dan (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2024-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Baicalin is a small molecule medication used to treat hepatitis. Our research group discovered that administering baicalin orally to mice following fecal microbiota transplantation from patients resistant to ICIs supported anti-PD-1 activity. However, the precise mechanisms behind this effect are pr...