An alpha-helix variant p.Arg156Pro in LMNA as a cause of hereditary dilated cardiomyopathy: genetics and bioinfomatics exploration

• Egile Nagusiak: Lei Chang (Egilea), Rong Huang (Egilea), Jianzhou Chen (Egilea), Guannan Li (Egilea), Guangfei Shi (Egilea), Biao Xu (Egilea), Lian Wang (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2023-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract LMNA gene encodes lamin A/C protein which participates in the construction of nuclear lamina, the mutations of LMNA result in a wide variety of diseases known as laminopathies. LMNA-related dilated cardiomyopathy(LMNA-DCM) is one of the more common laminopathy which characterized by progres...