An alpha-helix variant p.Arg156Pro in LMNA as a cause of hereditary dilated cardiomyopathy: genetics and bioinfomatics exploration

• Asıl Yazarlar: Lei Chang (Yazar), Rong Huang (Yazar), Jianzhou Chen (Yazar), Guannan Li (Yazar), Guangfei Shi (Yazar), Biao Xu (Yazar), Lian Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2023-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract LMNA gene encodes lamin A/C protein which participates in the construction of nuclear lamina, the mutations of LMNA result in a wide variety of diseases known as laminopathies. LMNA-related dilated cardiomyopathy(LMNA-DCM) is one of the more common laminopathy which characterized by progres...