Antisense oligonucleotide treatment produces a type I interferon response that protects against diet-induced obesity
Objective: In mouse models, deficiency of TTC39B (T39) decreases hepatic lipogenic gene expression and protects against diet-induced steatohepatitis. While assessing the therapeutic potential of antisense oligonucleotides (ASOs) targeting T39, we discovered an unexpected weight loss phenotype. The o...
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Asıl Yazarlar: | , , , , , , , , |
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Materyal Türü: | Kitap |
Baskı/Yayın Bilgisi: |
Elsevier,
2020-04-01T00:00:00Z.
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Yer Numarası: |
A1234.567 |
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Kopya Bilgisi 1 | Kütüphanede |