JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase (DGAT) 1 inhibitor, improves glucose metabolism in diet-induced obesity and genetic T2DM mice

• Asıl Yazarlar: Daisuke Tomimoto (Yazar), Chihiro Okuma (Yazar), Yukihito Ishii (Yazar), Akio Kobayashi (Yazar), Takeshi Ohta (Yazar), Makoto Kakutani (Yazar), Tsuneo Imanaka (Yazar), Nobuya Ogawa (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2015-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Type 2 diabetes mellitus (T2DM) arises primarily due to lifestyle factors and genetics. A number of lifestyle factors are known to be important in the development of T2DM, including obesity. JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase 1 inhibitor, reduced body weight depending on dietar...