JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase (DGAT) 1 inhibitor, improves glucose metabolism in diet-induced obesity and genetic T2DM mice

• मुख्य लेखकों: Daisuke Tomimoto (लेखक), Chihiro Okuma (लेखक), Yukihito Ishii (लेखक), Akio Kobayashi (लेखक), Takeshi Ohta (लेखक), Makoto Kakutani (लेखक), Tsuneo Imanaka (लेखक), Nobuya Ogawa (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2015-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Type 2 diabetes mellitus (T2DM) arises primarily due to lifestyle factors and genetics. A number of lifestyle factors are known to be important in the development of T2DM, including obesity. JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase 1 inhibitor, reduced body weight depending on dietar...