Contraction-stimulated glucose transport in muscle is controlled by AMPK and mechanical stress but not sarcoplasmatic reticulum Ca2+ release

• Главные авторы: Thomas E. Jensen (Автор), Lykke Sylow (Автор), Adam J. Rose (Автор), Agnete B. Madsen (Автор), Yeliz Angin (Автор), Stine J. Maarbjerg (Автор), Erik A. Richter (Автор)
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• Опубликовано: Elsevier, 2014-10-01T00:00:00Z.
• Предметы: article
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Understanding how muscle contraction orchestrates insulin-independent muscle glucose transport may enable development of hyperglycemia-treating drugs. The prevailing concept implicates Ca2+ as a key feed forward regulator of glucose transport with secondary fine-tuning by metabolic feedback signals...