Reno-protective effect of mangiferin against methotrexate-induced kidney damage in male rats: PPARγ-mediated antioxidant activity

• Auteurs principaux: Seba Hassan Attia (Auteur), Shimaa Mustafa Elshazly (Auteur), Mahmoud Mohamed Abdelaal (Auteur), Eman Soliman (Auteur)
• Format: Livre
• Publié: Elsevier, 2022-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Methotrexate (MTX) is an immunosuppressant used for the treatment of cancer and autoimmune diseases. MTX has a major adverse effect, acute kidney injury, which limits its use. Mangiferin (MF) is a natural bioactive xanthonoid used as a traditional herbal supplement to boost the immune system due to...