Reno-protective effect of mangiferin against methotrexate-induced kidney damage in male rats: PPARγ-mediated antioxidant activity

• Váldodahkkit: Seba Hassan Attia (Dahkki), Shimaa Mustafa Elshazly (Dahkki), Mahmoud Mohamed Abdelaal (Dahkki), Eman Soliman (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2022-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Methotrexate (MTX) is an immunosuppressant used for the treatment of cancer and autoimmune diseases. MTX has a major adverse effect, acute kidney injury, which limits its use. Mangiferin (MF) is a natural bioactive xanthonoid used as a traditional herbal supplement to boost the immune system due to...