Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity

• Príomhchruthaitheoirí: Robina Khan Niazi (Údar), Anette P Gjesing (Údar), Mette Hollensted (Údar), Christian Theil Have (Údar), Niels Grarup (Údar), Oluf Pedersen (Údar), Asmat Ullah (Údar), Gulbin Shahid (Údar), Wasim Ahmad (Údar), Asma Gul (Údar), Torben Hansen (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: BMC, 2018-11-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Abstract Background Mutations in the genes encoding leptin (LEP), the leptin receptor (LEPR), and the melanocortin 4 receptor (MC4R) are known to cause severe early-onset childhood obesity. The aim of the current study was to examine the prevalence of damaging LEP, LEPR, and MC4R mutations in Pakist...