Rational drug repurposing for alzheimer's treatment using in-silico ligand and structure-based approaches

• Main Authors: Karishma Rathi (Author), Ravindra Wavhale (Author), Ritesh Bhole (Author), Vaishali Undale (Author), Somdatta Chaudhari (Author)
• Format: Book
• Published: Universidade de São Paulo, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Alzheimer's disease is a devastating neurodegenerative disorder characterized by memory loss and cognitive decline. New AD treatments are essential, and drug repositioning is a promising approach. In this study, we combined ligand-based and structure-based approaches to identify potent...