Rational drug repurposing for alzheimer's treatment using in-silico ligand and structure-based approaches

• 主要な著者: Karishma Rathi (著者), Ravindra Wavhale (著者), Ritesh Bhole (著者), Vaishali Undale (著者), Somdatta Chaudhari (著者)
• フォーマット: 図書
• 出版事項: Universidade de São Paulo, 2024-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Alzheimer's disease is a devastating neurodegenerative disorder characterized by memory loss and cognitive decline. New AD treatments are essential, and drug repositioning is a promising approach. In this study, we combined ligand-based and structure-based approaches to identify potent...