Rational drug repurposing for alzheimer's treatment using in-silico ligand and structure-based approaches

• Egile Nagusiak: Karishma Rathi (Egilea), Ravindra Wavhale (Egilea), Ritesh Bhole (Egilea), Vaishali Undale (Egilea), Somdatta Chaudhari (Egilea)
• Formatua: Liburua
• Argitaratua: Universidade de São Paulo, 2024-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Alzheimer's disease is a devastating neurodegenerative disorder characterized by memory loss and cognitive decline. New AD treatments are essential, and drug repositioning is a promising approach. In this study, we combined ligand-based and structure-based approaches to identify potent...