Rational drug repurposing for alzheimer's treatment using in-silico ligand and structure-based approaches

• Κύριοι συγγραφείς: Karishma Rathi (Συγγραφέας), Ravindra Wavhale (Συγγραφέας), Ritesh Bhole (Συγγραφέας), Vaishali Undale (Συγγραφέας), Somdatta Chaudhari (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Universidade de São Paulo, 2024-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Alzheimer's disease is a devastating neurodegenerative disorder characterized by memory loss and cognitive decline. New AD treatments are essential, and drug repositioning is a promising approach. In this study, we combined ligand-based and structure-based approaches to identify potent...