The emerging role of irisin in experimentally induced arthritis: a recent update involving HMGB1/MCP1/Chitotriosidase I-mediated necroptosis

• Hauptverfasser: Rowida Raafat Ibrahim (Verfasst von), Noha M. Shafik (Verfasst von), Rasha Osama El-Esawy (Verfasst von), Mervat H. El-Sakaa (Verfasst von), Heba M. Arakeeb (Verfasst von), Radwa Mahmoud El-Sharaby (Verfasst von), Dina Adam Ali (Verfasst von), Omnia Safwat El-deeb (Verfasst von), Sara Ragab Abd El-Khalik (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Objectives Necroptosis is a tightly adjusted inflammatory necrotizing cell death signaling pathway that participates in pathogenesis of discrete diseases as rheumatoid arthritis (RA). Irisin is a myokine with immuno-modulatory effect. Evaluation of irisin efficiency as a novel therapeutic agent in e...