Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition
Abnormal activation of the mammalian target of rapamycin (mTOR) signaling pathway has been observed in a variety of human cancers. Therefore, targeting of the mTOR pathway is an attractive strategy for cancer treatment and several mTOR inhibitors, including AZD8055 (AZD), a novel dual mTORC1/2 inhib...
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Main Authors: | Aimin Yang (Author), Xia Xiao (Author), Mingfeng Zhao (Author), Amanda C. LaRue (Author), Bradley A. Schulte (Author), Gavin Y. Wang (Author) |
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Format: | Book |
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Hindawi Limited,
2015-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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