In Vitro PIG-A Gene Mutation Assay in Human B-Lymphoblastoid TK6 Cells
The X-linked PIG-A gene is involved in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. PIG-A mutant cells fail to synthesize GPI and to express GPI-anchored protein markers (e.g., CD59 and CD55). In recent years, in vitro PIG-A assay has been established based on the high conservatio...
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Georg Thieme Verlag KG,
2021-06-01T00:00:00Z.
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