Emodin Protects Against Lipopolysaccharide-Induced Acute Lung Injury via the JNK/Nur77/c-Jun Signaling Pathway

• Main Authors: Pei Xie (Author), Li-Jun Yan (Author), Hong-Ling Zhou (Author), Hui-Hui Cao (Author), Yuan-Ru Zheng (Author), Zi-Bin Lu (Author), Hua-Yi Yang (Author), Jia-Mei Ma (Author), Yu-Yao Chen (Author), Chuying Huo (Author), Chunyang Tian (Author), Jun-Shan Liu (Author), Lin-Zhong Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Acute lung injury (ALI) is a serious inflammatory disease with clinical manifestations of hypoxemia and respiratory failure. Presently, there is no effective treatment of ALI. Although emodin from Rheum palmatum L. exerts anti-ALI properties, the underlying mechanisms have not been fully...