Emodin Protects Against Lipopolysaccharide-Induced Acute Lung Injury via the JNK/Nur77/c-Jun Signaling Pathway

• Principais autores: Pei Xie (Autor), Li-Jun Yan (Autor), Hong-Ling Zhou (Autor), Hui-Hui Cao (Autor), Yuan-Ru Zheng (Autor), Zi-Bin Lu (Autor), Hua-Yi Yang (Autor), Jia-Mei Ma (Autor), Yu-Yao Chen (Autor), Chuying Huo (Autor), Chunyang Tian (Autor), Jun-Shan Liu (Autor), Lin-Zhong Yu (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Acute lung injury (ALI) is a serious inflammatory disease with clinical manifestations of hypoxemia and respiratory failure. Presently, there is no effective treatment of ALI. Although emodin from Rheum palmatum L. exerts anti-ALI properties, the underlying mechanisms have not been fully...